INSTRUMENTS AVAILABLE IN PHARMACOLOGY AND TOXICOLOGY LAB

Name of Instrument

Maker (Model No.)

Hot Plate Analgesiometer

Specifications

Ø Footswitch to start, stop and ready the instrument.

Ø Temperature sensor is located in the centre of the black anodized plate.

Ø Keypad, allow all parameters to be entered for the test

IITC Life science (39)

Application

Used to measure the analgesic activity of Rodents

Digital Paw Pressure Randall Selitto Instrument Mice and Rats

Electronic Randall Selitto test system

Ø Footswitch are provided to for operating the instruments.

Ø Pressure applicaator

IITC Life science (2500)

Application

To measure the pain threshold

Digital Plethysmometer

Specifications

Ø Footswitch are provided to for operating the instruments.

Ø Acrylic stand with Electronic unit to measure the volume

IITC Life science (2500)

Application

To measure the effectiveness of anti-inflammatory agents to reduce edema conditions digitally on both mice and rat

Microprobe Digital Thermometer

Specifications

Ø BAT-12 reads to-100°C to +200°C with 0.1 resolutions.

Ø Super Accuracy and Fast Readings

Ø Auto Corrected for Ambient Temperature

Physitemp instrument INC Model (BAT-12)

Application

For measuring the temperature

Rotamix-5

Specifications

Ø Number of Exercise Lanes: 4

Ø Rotarod Spindle Speed Range: 0 - 99.9 RPM

Ø Acceleration Increments: 0.1 RPM per second. to 20.0 RPM per second

Ø Mouse Spindle Dimensions: 3.0 cm x 9.5 cm

Ø Rat Spindle Dimensions: 7.0 cm x 9.5 cm

Ø Fall height From Rod center: 44.5 cm

Ø Unit Dimensions(LxWxH): 61cm X 56cm X 77cm

Ø Animal Detection Method: Scanning infrared beam(32) sensors monitor animals absence from rod assembly.

Ø Communication (optional): RS-232 to RS422(CIBUS) Multi drop. (Max of 64

devices)

Columbus Instruments (0254-2002L)

Application

Muscle relaxant activity of rodents

PACS-30

Specifications

Ø Performs both Active and Passive Avoidance Testing

Ø Supports operation of up to 30 boxes

Ø Standard visual and acoustical stimuli

Ø Avoidance Cage Dimensions: 19"L x 9"W x 10.75"H (48cm x 23cm x 27cm)

Ø Motion Detection Method: Multiple Infrared Beams

Columbus Instruments

Application

Used for Active and passive avoidance behavior

Opto-Varimex-4

Specifications

Ø Number of beam light are 4 to 6, depending on the sensor size and type

Ø Beam diameter is 0.0125 inches and beam length is 875 nm.

Ø Control unit 35 cm*29 cm* 10 cm

Columbus Instruments

Application

Activity of drugs on rodents

Digital stereo taxis

Specifications

Ø EZ clips,Non sterile, Box/200

Ø EZ clip applier

Ø EZ remover

Ø Dermo moto tool

Ø The large LED display is also useful for surgeries performed in low light, or constrained environments where reading the vernier scale is difficult.

Stoelting (51500D)

Application

It is used to perform surgeries on both mice and rat with greater speed and accuracy due to the digital display

Sociability Apparatus

Specifications

Ø Main enclosures divided in to 3 components.

Ø Width, depth and height is

60 cm*40cm*22cm

Ø Connected to Any Maze video tracking software.

Stoelting (60450)

Application

It is used to perform autistic-like behaviors in rodents

Open field

Specifications

Ø The open field arena had semi-transparent (frosted) Perspex

walls, with an internal diameter

of 40 x 40 cm.

Ø Connected to Any Maze video tracking software.

Stoelting (60100)

Application

The Open Field is broadly used to assess exploratory

behavior, and is validated for use in the measurement of anxiety-related

Behaviors.

T maze for Mouse and Rat

Specifications

Ø Walls fit solidly in slotted base, but lift off for easy cleaning.

Ø base plate is grey and non reflective

Ø Connected to Any Maze video tracking software.

Stoelting (60181,60281)

Application

It is used largely in preference and spatial learning tasks.

Elevated Plus Maze ANY-maze Bundle

Elevated Plus maze for rat and mouse

Specifications

Ø Lane width,Arm length, Wall height, Leg height are 10*50*40*40cm

for Rat and 5cm*35*15*40cm for Mouse.

Ø Walls fit solidly in slotted base, but lift off for easy cleaning.

Ø base plate is grey and non reflective

Ø Connected to Any Maze video tracking software.

Stoelting (60140,60240)

Application

It is used to assess anxiety-like behavior in Rodent. The maze exploits the conflict between the innate fear that rodents have of

Open areas versus their desire to explore novel environments.

Animal+Respirator-Compact

TSE Animal Respirator Compact

Specifications

Ø The individual adjustment of ventilation parameters like as breathing frequency, inspiration length, plateau length - and pressure parameters such as EIP value (end-inspiratory pressure), EIP Limit (maximal trachea pressure during inspiration), etc.

is possible

TSE system

Application

It is used for the respiration of small laboratory animals

such as mice and young rats

Rodent shocker

Specifications

Ø Stimulation Frequency 50 Hz or 60 Hz according to supply frequency

Ø Stimulus Duration 0.1 sec to 9.9 sec in steps of 0.1 sec, selected after

Ø pressing a button, the selected time is indicated

Ø Constant current, fully floating

Output Current 0 to 300 mA, 0 to 150 mA, 0 to 100 mA

Ø Limitation of Maximum 250 V, 500 V, 750 V in 3 steps, selected by button

HSE Haverd instrument (Type 221)

Application

Testing the anticonvulsant drug on mice and rat by using eye and ear electrode

Radnoti Lagendorff system

Specifications

Ø Stand Assembly

Ø Water jacket heart chamber with a collecting trap perfusate manifolds and valves

Ø Water jacket reservoir with aerators and peristaltic and thermal circulator pump

Ø Power Lab 26 T and software

AD Instruments (PTK28-220)

Application

It is used the examination of cardiac contractile strength and heart rate without the complications of an intact animal.

8 Channel Organ bath

with Power Lab

Specifications

Ø Automatic filling and emptying of organ bath tube using controller knobs on control panel

Ø Compact and robust design

Ø Precise control over bubbling speed from control panel

Ø Maintenance Free- Use of Teflon stopcock based system in place of solenoid valve

Ø Available with analogue and digital temperature controller

Ø No leakage- Thick perspex single joint tank

Ø No glass parts- Organ bath tube is made of P. P. And reservoir coil is made of perspex making system breakage free and maintenance free

Ø Uniform Temperature- Inbuilt water circulation pump for uniform temperature control

Orchid Scientific (PTK28-220)

Application

In vitro response of drug in Isolated tissue.

Power Lab 26T with Bridge AMP

AD Instruments, Australia

Application

Recording the Blood pressure, ECG and HRV (Diastolic, Systolic, pulse pressure)

Mettler Toledo ML204 NewClassic Analytical Balance with Draft Shield, 220 g Capacity, 0.0001 g Readability

Digital Balance

Specifications

Ø Capacity 220 grams

Ø Display Backlit Display

Ø Overall Height 331 mm

Ø Overall Length 290 mm

Ø Overall Width 193 mm

Ø Readout Accuracy 0.0001 grams

Ø Size 220g Capacity

Mettler-Toledo (ML204/A01)

Application

Weighing the chemical

Optical Upright Microscope

Specifications

Ø Binocular Research Microscope

Ø Anti fungus optics and High performance aspheric lenses

Ø SMPS circuit Illumination System

Ø Parfocality & precentred objectives

Olympus (CH 20i)

Application

Used for microscopic study

Gel Electrophoresis unit (vertical and horrizontal setup) and Blotting Assembly

Specifications

Ø Sub- cell ^R GT Agarose gel electrophoresis

Ø Mini protein^R Tetra cell

Ø Trans-Blot^R SD Semi-Dry Electrophoretic Transfer Cell

Bio-Rad

Application

Use for electrophoresis and transfer of DNA,RNA and protein

UV Transilluminator

Specifications

Ø Sub- cell ^R GT Agarose gel electrophoresis

Ø Mini protein^R Tetra cell

Ø Trans-Blot^R SD Semi-Dry Electrophoretic Transfer Cell

Ge Nei^TM (107171)

Application

Use for visuliading the DNA

Multiscan FC

Specifications

Ø Plate Type 96-well plates

Ø Light Source Quartz-halogen lamp

Ø Detector Type Photodetector

Ø Wavelength Selection Filters

Ø Wavelength Range 340 to 850nm

Ø Filters 8-position filter wheel; filters installed was 405 nm,450 nm,492 nm,550nm,620nm,690nm

Thermofisher Scintific

Application

Immunoassays (ELISA), protein assays, endotoxins, cytotoxicity and proliferation assay

CO₂Incubator

Ø Temperature range from 4°C above ambient to 50°C.

Ø Sealed, inner glass door allows observation of samples without disturbing cultures.

Ø RS-232 and 25mm access ports for use with external instruments.

Ø IR sensor comes standard for specific and accurate control of CO2 levels. IR sensor comes standard for specific and accurate control of CO2 levels.

Eppendorf

(C017EM601895)

Use for cell culture and bacteria incubation